منابع مشابه
Editorial Cardiac work and efficiency
See article by Kiriazis and Gibbs [1] (pages 111 –119) two parts, activation and basal oxygen consumption. The in this issue. first depends on excitation–contraction coupling and is proportional to cardiac contractility. For the quiescent muscle the PVA and the oxygen cost of activation both are zero. The remaining part results from all other processes 1. Work output and efficiency of the heart...
متن کاملCardiac work and contractility.
It has been customary to regard the heart as a pump maintaining the flow of blood, and to assess the work done by the heart from the pressure and volume of blood leaving the ventricles. While correct in physical terms, measurement of external cardiac work in this way is a poor index of the myocardial oxygen consumption which is related to the work done by the ventricular muscle. Systolic pressu...
متن کاملThe effect of hexamethonium bromide upon coronary flow, cardiac work and cardiac efficiency in normotensive and renal hypertensive dogs.
Hexamethonium bromide in normotensive and renal hypertensive dogs resulted in significant reductions in arterial blood pressure, cardiac output and cardiac work. Ihe decrease in cardiac output relative to that in blood pressure suggests that the blood pressure reduction was largely due to the decrease in cardiac output. There was a decrease in coronary flow accompanied by an increase in myocard...
متن کاملFree fatty acid depletion acutely decreases cardiac work and efficiency in cardiomyopathic heart failure.
BACKGROUND Metabolic modulators that enhance myocardial glucose metabolism by inhibiting free fatty acid (FFA) metabolism may improve cardiac function in heart failure patients. We studied the effect of acute FFA withdrawal on cardiac function in patients with heart failure caused by idiopathic dilated cardiomyopathy (IDCM). METHODS AND RESULTS Eighteen fasting nondiabetic patients with IDCM ...
متن کاملEffects of sodium nitroprusside upon cardiac work, efficiency, and substrate extraction in severe left ventricular failure.
In nine patients with severe left ventricular failure caused by coronary artery disease or congestive cardiomyopathy, left ventricular pressure, cardiac output, coronary sinus blood flow, and myocardial substrate extraction were measured before and during infusion of sodium nitroprusside. Infusion of 55 ,ug/min reduced left ventricular systolic and end-diastolic pressures, peripheral resistance...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2000
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(00)00176-0